Zoloft

· Trade Name
ZOLOFT

· Generic Name
Sertraline

· Drug Class
Anti-depressant SSRI (Selective Serotonin Reuptake Inhibitor)

· How It Works
Selectively inhibits serotonin reuptake in the brain.

· Serious Side Effects
suicidality
worsening depression
serotonin syndrome
neuroleptic malignant syndrome
withdrawal syndrome
mania
seizures
hyponatremia
SIADH
abnormal bleeding/altered platelet fxn
glaucoma, acute angle-closure
priapism
anaphylactoid reactions
hypoglycemia
neonatal persistent pulm. HTN (>20 wk gest)
neonatal serotonin syndrome (3rd trimester)
neonatal withdrawal (3rd trimester)

· Common Side Effects
nausea
headache
insomnia
diarrhea
dry mouth
ejaculatory dysfunction
somnolence
asthenia
tremor
dyspepsia
anorexia
constipation
decreased libido
nervousness
anxiety
rash
abnormal vision

Posted on February 12, 2009

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