Gallstones

Definition
· Gallstones are the disorder of cholesterol stone formation within the biliary track.

Overview
· Gallstones are very common and occur in up to 36% of people and do not commonly cause symptoms.
· Gallstones are 3 times more common in women.
· Gallstones are more common with:
· Crohn’s disease
· gastric surgery
· obesity
· pregnancy
· sickle cell anemia
· thalassemia

Types
· Gallstones are predominantly made of cholesterol and biliary salts and calcium.

Symptoms
· right upper quadrant abdominal pain
· upper abdominal pain
· indigestion
· abdominal pain after a high fat meal

Complications
· infection of the gallbladder
· necrosis of the gallbladder wall
· rupture of the gallbladder

Treatment
· Surgical removal of the gallbladder

References
Gallstones: Genetics versus environment. Ann Surg 235:842, 2002.  [PMID: 12035041]

Posted on September 24, 2008

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