Diabetes, Type I
• Definition
· Diabetes, Type I is the disease of high blood glucose levels.
· Diabetes, Type I is the disease of no measurable blood insulin levels.
· Diabetes, Type I is diagnose by a fasting blood glucose greater than 126.
• Overview
· Diabetes, Type I onset is usually at ages of five to six years or prior to starting puberty- about 13 years of age.
· Diabetes, Type I affects one million people (as opposed to Type II Diabetes which affects 17 million people)
· For reasons which remain unclear to researchers, the frequency of Diabetes, Type I is increasing worldwide by about three percent per year.
· Diabetes, Type I is caused by an auto-immune destruction of the pancreatic islet B-cells (damage to or destruction of the cells in the pancreas that make insulin).
• Symptoms
· Diabetes, Type I symptoms include:
· Increased appetite (polyphagia) with weight loss
· Increased thirst (polydipsia)
· Increased urination (polyuria)
· Paresthesias (tingling)
· Recurrent blurred vision
· Vaginal fungal infections
· Dehydration
• Complications
· Diabetes, Type I complications include:
· Diabetic kidney disease
· Diabetic neuropathy
· Diabetic ketoacidosis
· Diabetic retinopathy
· Cataracts
· Nephropathy
· Heart disease
· Cerebral vascular disease
• Treatment
· Insulin
References
Daneman D. Type 1 diabetes. Lancet. 2006;367:847. [PMID: 16530579]
Torpy JM et al. JAMA patient page: Type 1 diabetes. JAMA. 2003;290:2216. [PMID: 14570956]
Posted on September 24, 2008

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